Yoshikatsu Kanai Selected Research

Amino Acid Transport System L

4/2009	System L amino acid transporter inhibitor enhances anti-tumor activity of cisplatin in a head and neck squamous cell carcinoma cell line.
9/2008	Characterization of amino acid transport system L in HTB-41 human salivary gland epidermoid carcinoma cells.
5/2005	Amino acid transport system L is differently expressed in human normal oral keratinocytes and human oral cancer cells.
9/2002	Characterization of the system L amino acid transporter in T24 human bladder carcinoma cells.

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Yoshikatsu Kanai Research Topics

Disease

88	Neoplasms (Cancer) 01/2022 - 03/2002
9	Glioma (Gliomas) 04/2020 - 03/2002
9	Gout 04/2016 - 09/2003
8	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 11/2011 - 04/2009
7	Carcinoma (Carcinomatosis) 01/2020 - 09/2002
6	Prostatic Neoplasms (Prostate Cancer) 09/2021 - 01/2009
6	Squamous Cell Carcinoma of Head and Neck 11/2015 - 05/2004
6	Squamous Cell Carcinoma (Epidermoid Carcinoma) 02/2009 - 09/2003
5	Mouth Neoplasms (Oral Cancer) 01/2014 - 03/2004
4	Inflammation (Inflammations) 01/2020 - 03/2016
4	Obesity 10/2018 - 06/2015
4	Renal hypouricemia 01/2014 - 09/2003
3	Neoplasm Metastasis (Metastasis) 01/2022 - 04/2010
3	Breast Neoplasms (Breast Cancer) 01/2022 - 02/2012
3	Biliary Tract Neoplasms (Biliary Tract Cancer) 02/2021 - 10/2013
3	Lymphatic Metastasis 01/2018 - 09/2010
3	Adenocarcinoma 01/2018 - 10/2009
3	Osteosarcoma (Osteogenic Sarcoma) 11/2017 - 05/2006
3	Starvation 01/2017 - 03/2007
3	Hepatocellular Carcinoma (Hepatoma) 11/2016 - 07/2009
3	Cardiovascular Diseases (Cardiovascular Disease) 04/2016 - 09/2003
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 04/2013 - 10/2003
3	Colonic Neoplasms (Colon Cancer) 01/2010 - 01/2006
2	Multiple Myeloma 01/2022 - 11/2014
2	Pancreatic Neoplasms (Pancreatic Cancer) 03/2019 - 01/2015
2	Endometrial Neoplasms (Endometrial Cancer) 01/2017 - 04/2014
2	Infections 11/2016 - 05/2014
2	Fetal Growth Retardation (Intrauterine Growth Retardation) 04/2016 - 02/2013
2	Adenocarcinoma of Lung 01/2015 - 01/2011
2	Acute Kidney Injury (Acute Renal Failure) 01/2014 - 12/2008
2	Hypoxia (Hypoxemia) 12/2011 - 01/2011
2	Head and Neck Neoplasms (Head and Neck Cancer) 04/2009 - 12/2008
2	Hyperuricemia 04/2008 - 09/2003
2	Carcinogenesis 02/2008 - 09/2003
2	Blue diaper syndrome 04/2005 - 01/2002
2	Stroke (Strokes) 02/2004 - 10/2003
2	Ischemia 02/2004 - 10/2003

Drug/Important Bio-Agent (IBA)

85	Amino Acid Transport Systems (Amino Acid Transporter)IBA 01/2022 - 03/2002
20	Amino Acids FDA Link 01/2022 - 04/2005
13	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2020 - 12/2008
11	Neutral Amino AcidsIBA 01/2019 - 03/2004
11	Uric Acid (Urate)IBA 04/2016 - 09/2003
10	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2007
9	Essential Amino AcidsIBA 09/2021 - 03/2004
9	AcidsIBA 04/2020 - 08/2006
8	Large Neutral Amino Acid-Transporter 1IBA 01/2022 - 09/2007
8	Leucine (L-Leucine)FDA Link 02/2017 - 09/2002
7	Tyrosine (L-Tyrosine)FDA Link 03/2021 - 11/2010
6	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 01/2011
6	Glutamic Acid (Glutamate)FDA Link 01/2017 - 10/2003
6	Indicators and Reagents (Reagents)IBA 11/2015 - 05/2004
6	Heavy Chain Fusion Regulatory Protein 1IBA 09/2010 - 05/2004
5	Mechanistic Target of Rapamycin Complex 1IBA 01/2022 - 04/2013
5	2- amino- 3- (4- ((5- amino- 2- phenylbenzo(d)oxazol- 7- yl)methoxy)- 3,5- dichlorophenyl)propanoic acidIBA 02/2021 - 01/2010
4	TOR Serine-Threonine KinasesIBA 02/2017 - 01/2011
4	urate transporterIBA 04/2016 - 09/2003
4	Protein Isoforms (Isoforms)IBA 03/2016 - 08/2012
4	Biomarkers (Surrogate Marker)IBA 12/2014 - 01/2009
4	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 01/2014 - 12/2008
4	Amino Acid Transport System LIBA 04/2009 - 09/2002
3	Surface Antigens (Surface Antigen)IBA 01/2022 - 01/2019
3	Phenylalanine (L-Phenylalanine)FDA Link 12/2020 - 03/2019
3	Pharmaceutical PreparationsIBA 01/2019 - 04/2007
3	Biological ProductsIBA 12/2014 - 02/2006
3	Deoxyglucose (2 Deoxy D glucose)IBA 10/2013 - 11/2007
3	ErbB Receptors (EGF Receptor)IBA 12/2011 - 01/2011
3	AntigensIBA 08/2006 - 03/2002
2	Hormones (Hormone)IBA 01/2022 - 05/2016
2	ProteomeIBA 01/2022 - 02/2021
2	Monoclonal AntibodiesIBA 01/2022 - 01/2009
2	Aromatic Amino Acids (Aromatic Amino Acid)IBA 01/2022 - 01/2002
2	Androgen Receptors (Androgen Receptor)IBA 09/2021 - 05/2016
2	DNA (Deoxyribonucleic Acid)IBA 03/2021 - 02/2008
2	AndrogensIBA 01/2021 - 04/2013
2	RNA (Ribonucleic Acid)IBA 01/2021 - 09/2007
2	Organic Anion TransportersIBA 12/2020 - 04/2008
2	TurpentineIBA 01/2020 - 02/2017
2	CationsIBA 12/2017 - 12/2009
2	Cisplatin (Platino)FDA LinkGeneric 02/2017 - 04/2009
2	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 02/2017 - 04/2009
2	Sirolimus (Rapamycin)FDA Link 01/2017 - 12/2011
2	sodium-bile acid cotransporterIBA 11/2016 - 05/2014
2	Small Interfering RNA (siRNA)IBA 03/2016 - 07/2006
2	PlatinumIBA 04/2014 - 11/2011
2	Branched-Chain Amino AcidsIBA 04/2013 - 03/2007
2	TensinsIBA 12/2011 - 01/2011
2	Phosphoric Monoester Hydrolases (Phosphatases)IBA 12/2011 - 01/2011
2	HexokinaseIBA 12/2011 - 01/2011
2	Messenger RNA (mRNA)IBA 12/2010 - 03/2007
2	SodiumIBA 06/2010 - 03/2002
2	3,4,5,3',4'-pentachlorobiphenylIBA 02/2006 - 08/2005
2	anthraceneIBA 08/2005 - 09/2003
2	Amino Acid Transport System X-AG (Glutamate Transporter)IBA 02/2004 - 10/2003
1	EpitopesIBA 01/2022
1	human ERBB2 proteinIBA 01/2022
1	SugarsIBA 01/2022
1	Phosphate Transport Proteins (Phosphate Transporter)IBA 01/2022

Therapy/Procedure

25	Therapeutics 01/2022 - 03/2004
5	Drug Therapy (Chemotherapy) 01/2018 - 04/2007
2	Boron Neutron Capture Therapy 01/2022 - 03/2019